The basic difference between the two is the user interface.
Both plesk and cpanel are quire fast, secure, and reliable.
However, they differ in a few aspects:
Plesk
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Advantages
-Plesk features support automation
- more plug-ins
- Plesk is cheaper
- Plesk Supports SuSE Linux.
Disadvantages
-user interface is slightly harder to use and
customise
cPanel
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Advantages
- different rtypes of s/w available integrate with it.
- Easy to use
Disadvantages
-Not supporting XML
- not supporting SuSE Linux
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